Tadalafil, commonly known under the brand name Cialis, is a phosphodiesterase type 5 (PDE5) inhibitor primarily used to treat erectile dysfunction (ED) and symptoms of benign prostatic hyperplasia (BPH) in men. However, a variant known as Femalefil, which contains Tadalafil, is marketed for addressing sexual dysfunction in women.

Mechanism of Action: Tadalafil Femalefil works by enhancing blood flow to the penis during sexual stimulation, facilitating an erection. It does this by inhibiting the enzyme PDE5, which breaks down cyclic guanosine monophosphate (cGMP), a molecule that promotes vasodilation. This mechanism is also beneficial in treating pulmonary arterial hypertension (PAH) by relaxing blood vessels in the lungs, thereby improving blood flow and reducing pressure.

Dosage and Administration: Tadalafil is available in tablet form and can be taken with or without food. For erectile dysfunction, it is typically taken as needed, about 30 minutes before sexual activity, and its effects can last up to 36 hours. For chronic conditions like BPH or PAH, it may be prescribed for daily use.

Side Effects: Common side effects include headaches, flushing, and digestive issues. Serious side effects can involve prolonged erections (priapism), vision changes, and hearing loss, necessitating immediate medical attention.

While Tadalafil has shown effectiveness in men, its use in women, particularly as Femalefil, is less established and should be approached with caution, ideally under medical supervision.